Jacob Misiorowski delivered a dominant performance on the mound, recording 11 strikeouts across five innings to power the Milwaukee Brewers to a commanding 14-2 victory over the Chicago White Sox in Thursday’s season opener for both clubs.
The hard-throwing Misiorowski (1-0) recovered quickly after surrendering a leadoff home run to Chase Meidroth, limiting Chicago to just one additional hit – a fourth-inning single – while issuing three walks over his 94-pitch appearance.
Misiorowski’s 11-strikeout effort established a new Opening Day franchise record for Milwaukee, breaking the previous mark of eight strikeouts that had been achieved three times, with Freddy Peralta being the most recent to accomplish the feat last season. The Brewers’ pitching staff collectively established a franchise milestone with 20 strikeouts, matching the major league standard for a nine-inning contest.
Offensively, Sal Frelick and Jake Bauers connected for home runs, with Bauers and William Contreras each contributing three RBIs. Six additional Brewers players recorded at least one RBI in the offensive explosion. For Chicago, Munetaka Murakami celebrated his major league debut with a home run.
Dodgers 8, Diamondbacks 2
Los Angeles continued their championship celebration with a decisive victory over visiting Arizona, as Andy Pages launched a three-run homer and Yoshinobu Yamamoto delivered six solid innings on the mound.
Will Smith added a home run while driving in three runs for the Dodgers, who honored their back-to-back World Series championships by displaying both the 2024 and 2025 trophies on the field during pre-game ceremonies. Yamamoto (1-0) struck out six batters while surrendering two runs on five hits without issuing a walk.
Arizona’s Geraldo Perdomo contributed two hits, including a two-run homer. Diamondbacks starter Zac Gallen struggled through four-plus innings, allowing four runs on five hits.
Guardians 6, Mariners 4
Rookie Chase DeLauter made an immediate impact in his first regular-season appearance, belting two home runs to lead Cleveland past Seattle.
Jose Ramirez delivered the decisive blow with a two-out, two-run double in the seventh inning to break the tie for the Guardians. Relief pitcher Connor Brogdon (1-0) earned the victory, while Cade Smith secured the save with a perfect ninth inning.
Seattle’s Dominic Canzone matched DeLauter with two solo homers, and Brendan Donovan and Luke Raley each added solo shots for the Mariners.
Tigers 8, Padres 2
Kevin McGonigle made baseball history by doubling in his first two major league at-bats and finished with a 4-for-5 performance as Detroit defeated San Diego on the road.
Dillon Dingler homered and knocked in three runs for the Tigers. Starting pitcher Tarik Skubal (1-0) was masterful over six innings, allowing three hits and one unearned run while walking none and striking out six.
Ramon Laureano provided San Diego’s lone bright spot with a solo homer. Padres starter Nick Pivetta (0-1) lasted only three innings, surrendering seven hits and six runs.
Phillies 5, Rangers 3
Cristopher Sanchez dominated with 10 strikeouts over six shutout innings, while Kyle Schwarber and Alec Bohm each homered to propel Philadelphia past Texas at home.
Fresh off signing a six-year contract extension on Sunday, Sanchez (1-0) capped his outstanding outing by striking out three consecutive batters in the sixth inning. He scattered three hits without issuing a walk.
Texas’s Jake Burger collected three hits, including a two-run homer in the ninth inning. Rangers starter Nathan Eovaldi (0-1) was charged with five runs on eight hits in 4 2/3 innings.
Red Sox 3, Reds 0
Garrett Crochet tossed six scoreless innings and Ceddanne Rafaela broke a scoreless deadlock in the seventh with an RBI single to guide Boston past Cincinnati on the road.
Roman Anthony collected three hits, while Trevor Story and Jarren Duran added insurance RBI singles in the ninth for the Red Sox. Crochet (1-0) allowed three hits, walked two and struck out eight, with Aroldis Chapman throwing a perfect ninth inning for the save.
Cincinnati’s Sal Stewart also recorded three hits, becoming the first Reds rookie since 1958 to collect three hits on Opening Day. Andrew Abbott matched Crochet’s effort with six shutout innings.
Orioles 2, Twins 1
Trevor Rogers threw seven scoreless innings and Baltimore scored late to defeat visiting Minnesota, giving Craig Albernaz a victory in his major league managerial debut.
Rogers held the Twins to three hits and four walks while striking out five. Adley Rutschman contributed two hits, including a double. In a decisive two-run seventh inning, Colton Cowser lifted a sacrifice fly and Blaze Alexander drove in a run in his first game wearing an Orioles uniform.
Minnesota managed only three singles through seven innings and lost Derek Shelton’s first game as the team’s manager. In the eighth, Byron Buxton tripled and scored on Luke Keaschall’s sacrifice fly. Twins starter Joe Ryan allowed one hit and two walks while striking out seven in 5 1/3 shutout innings.
Mets 11, Pirates 7
Brett Baty’s three-run triple highlighted a five-run first inning explosion, and New York chased defending National League Cy Young Award winner Paul Skenes after just two outs en route to a home victory over Pittsburgh.
Rookie Carson Benge and Francisco Alvarez connected for back-to-back homers in the sixth for the Mets, who improved their major league-best Opening Day record to 42-23. Pittsburgh’s Brandon Lowe launched two home runs in the losing effort.
Skenes (0-1) endured the shortest outing of his career, allowing five runs and four hits. Mets starter Freddy Peralta (1-0) permitted four runs while striking out seven over five innings.
Nationals 10, Cubs 4
Joey Wiemer, Jacob Young and Brady House all homered, and Washington’s bullpen contributed 5 1/3 innings of one-run relief to power the visiting Nationals past Chicago.
Wiemer went 3-for-3 to ignite an 11-hit offensive attack in his team debut, which also marked the first game for Nationals manager Blake Butera. House recorded two hits and two RBIs while CJ Abrams and Young each drove in two runs.
Chicago’s Michael Busch collected three hits and Pete Crow-Armstrong added two, but the Cubs struggled with runners in scoring position, going 4-for-19 while leaving nine men on base.
Angels 3, Astros 0
Mike Trout homered, walked three times and stole a base, while Jose Soriano struck out seven over six shutout innings to lead visiting Los Angeles past Houston.
The home run was the 405th of Trout’s career, as the three-time American League MVP made his club-record 14th Opening Day start in center field. Los Angeles captured their first road Opening Day victory since April 1, 2013, at Cincinnati in Kurt Suzuki’s major league managerial debut.
Nolan Schanuel also went deep and Jordan Romano pitched a scoreless ninth to earn a save. Houston’s AJ Blubaugh (0-1) surrendered one run on two hits over 2 1/3 innings while striking out three. Astros starter Hunter Brown scattered four singles and struck out nine over 4 2/3 shutout innings.
Cardinals 9, Rays 7
Alec Burleson capped an eight-run sixth inning with a two-run homer to help St. Louis rally for a victory against visiting Tampa Bay.
Burleson’s blast came after the Rays had scored six runs in the top half of the sixth to take a 7-1 lead. Burleson finished with three hits, scored twice and drove in two. Nathan Church contributed three hits, drove in two and robbed a home run, while JJ Wetherholt homered in his major league debut.
Tampa Bay’s Jonathan Aranda homered and singled. Yandy Diaz, Ben Williamson and Nick Fortes each collected three hits and scored one run, while Jonny DeLuca added two hits and two RBIs.
